These conformers have been used as building blocks for generating larger single stranded polymers, whose helical parameters we have calculated. We find that single stranded 'A' and 'B' form helices tend to be narrower and more tightly wound than the duplexes obtained in fibers 4,5. This is consistent with experimental observations on single stranded fibers of poly rC 6. We also find that the different sequences have different helix geometries. In addition, it is observed that large variations in helix geometry for a given sequence are achievable at little energetic cost. National Center for Biotechnology Information , U. Journal List Nucleic Acids Res v. Nucleic Acids Res.

Chiral selection of single helix formed by diblock copolymers confined in nanopores
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It is a type of smooth space curve with tangent lines at a constant angle to a fixed axis. Helices are important in biology , as the DNA molecule is formed as two intertwined helices , and many proteins have helical substructures, known as alpha helices. Helices can be either right-handed or left-handed. With the line of sight along the helix's axis, if a clockwise screwing motion moves the helix away from the observer, then it is called a right-handed helix; if towards the observer, then it is a left-handed helix. Handedness or chirality is a property of the helix, not of the perspective: a right-handed helix cannot be turned to look like a left-handed one unless it is viewed in a mirror, and vice versa. Most hardware screw threads are right-handed helices. The Z form of DNA is left-handed.
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